What is the relationship between fatty acids and fat?


Release time:

Dec 20,2024

Fats are broken down by lipase, producing glycerol and fatty acids

Fats are broken down by lipase, producing glycerol and fatty acids

A. Glycerol can be phosphorylated into glycerol phosphate, which enters the EMP pathway to generate Pyr and is oxidized;

B. Fatty acids are degraded by a series of enzymes, including β - oxidation, α - oxidation, and ω - oxidation. Among them, the more important pathway is β - oxidation, which refers to the production of a molecule of acetyl CoA by fatty acids under the catalysis of a series of enzymes. This is the main oxidation mode of fatty acids, followed by α - oxidation, and the products include CO2 and C3 compounds Next is ω - oxidation, which refers to the oxidation of fats to the last carbon atom to form carboxylic acids. After fatty acids become dicarboxylic acids, they can undergo β - oxidation from both ends, and the product is still acetyl CoA

The main product of fatty acid oxidation is acetyl CoA, which has two main pathways: 1. entering the glyoxylate cycle to convert into sugar. 2. entering the TCA cycle to be oxidized into CO2 and H2O and provide energy